MedPath

Study of Home Full Blood Count (FBC) Telemonitoring Device for Chemotherapy Patient

Not Applicable
Completed
Conditions
Cancer
Interventions
Device: Home Telemonitoring System (The Zodiac, Philips Health care)
Registration Number
NCT01436669
Lead Sponsor
Philips Healthcare
Brief Summary

The Zodiac, a Philips healthcare telemonitoring system has been devised to allow cancer patients receiving chemotherapy to test their blood count at home. It is anticipated that the system will allow patients and clinicians to reduce the toxic effects of chemotherapy by early diagnosis of neutropenia, anaemia and any associated complications of chemotherapy. It is also anticipated that the system will also allow clinicians to better manage the scheduling of chemotherapy regimes.

Detailed Description

Philips Healthcare has devised a new home full blood count (FBC) home telemonitoring system which will allow cancer patients receiving chemotherapy to test their blood count at home (haemoglobin, haematocrit, white cell count and neutrophil count). The system will also allow patients to record their temperature and symptoms. The Philips home telemonitoring system is called the Zodiac and consists of a telecommunications hub connected to a haematology analyser. The Hub connects to medical device software running on a remote server which controls the flow of information between the Hub and the clinician. This is designed to enable the patient to self test their full blood count in their home and transmit the data remotely to a clinician for review. In addition to testing their full blood count, the patients can input their temperature and any symptoms they have onto the device. The clinician will then be able to send appropriate instructions back to the patient. The Philips Zodiac system can also send a preprogrammed automated message based on the results of testing.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
20
Inclusion Criteria
  1. Male or female, age > 18.
  2. Able to give informed written consent in the English language.
  3. Diagnosis of cancer and receiving chemotherapy or with a planned chemotherapy start date within 2 weeks of enrolment.
  4. Patients who are able to perform finger prick test to obtain capillary blood.
Exclusion Criteria
  1. Inability to give informed consent due to mental capacity or language problems.
  2. Patients at risk of bruising or bleeding as a result of their disease or treatment.
  3. Patients at risk of bruising or bleeding due to anticoagulants (heparin or warfarin), aspirin or thrombocytopenia (platelet count <80).
  4. Patients with diabetes mellitus
  5. Patients with peripheral neuropathy

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Home MonitoringHome Telemonitoring System (The Zodiac, Philips Health care)All participants will receive a home telemonitoring system which will allow cancer patients receiving chemotherapy to test their blood count at home.
Primary Outcome Measures
NameTimeMethod
Capillary Blood Sample3 times per week for 6 weeks

To achieve a read out result of a full blood count (haemoglobin, haematocrit, white cell count and neutrophil count) from capillary blood obtained by finger prick and analysed in the Philips Zodiac system that varies by no more than 15% from a sample reported by the standard hospital based laboratory analyser for white cell count, haemoglobin and haematocrit using venous blood.

Secondary Outcome Measures
NameTimeMethod
Usability3 weeks and 6 weeks of use

To document the level of satisfaction and feasibility using questionnaires, in the use of the Philips Zodiac system (training, ease of use, performing a blood test and preference for home testing versus hospital testing)

Number of variances in neutrophil and haemoglobin3 times per week for 6 weeks

To measure the number of variances in the neutrophil and haemoglobin values between the Philips Zodiac system and hospital laboratory analyser, which could result in a different clinical decision being made based on the management of patients at risk of neutropenia and anaemia.

Performance Evaluation3 times per week for weeks 1-6

The questionnaire will assess the patients response to the flow of information via the server software, i.e. the ability of the Philips Zodiac system to provide the patient with a correct automated message or message from a clinician based on the results of the testing; the ability of patients to receive and understand the system messages; and, the satisfaction of patients with the Philips Zodiac System in terms of training issues, ease of use, performing a blood test, performing quality control tests and preference for home testing versus hospital testing.

Trial Locations

Locations (1)

Royal Marsden Hospital

🇬🇧

Belmont, Surrey, United Kingdom

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