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A Computer-Based System for Symptom Reporting in Patients With Cancer Undergoing Treatment

Not Applicable
Completed
Conditions
Caregiver
Malignant Neoplasm
Interventions
Other: Best Practice
Other: Computer Application
Other: Questionnaire Administration
Other: Quality-of-Life Assessment
Registration Number
NCT03979846
Lead Sponsor
Thomas Jefferson University
Brief Summary

This pilot trial studies the usability and usefulness of a computer-based system for reporting symptoms in patients with cancer undergoing treatment. Cancer patients undergoing cancer treatment are not always comfortable contacting the doctor when experiencing symptoms. A computer based platform, where patients can input symptoms, may seem less intrusive than a phone call and may improve patient access to care.

Detailed Description

PRIMARY OBJECTIVES:

I. To assess the usability and usefulness of a computer-based system for cancer patient symptom reporting.

SECONDARY OBJECTIVES:

I. To collect preliminary effectiveness data: quality of life outcomes with the Function Assessment of Cancer Therapy - General (FACT-G) and self-efficacy as measured by Chronic Disease Self-Efficacy Scale, Revised (CDSES-R).

OUTLINE: Participants are randomized to 1 of 2 arms.

ARM I: Participants receive usual care for 3 weeks, then use a computer-based symptom reporting system for 3 weeks. Caregivers may assist patients in the use of the computer based symptoms reporting system.

ARM II: Participants use a computer-based symptom reporting system for 3 weeks, then receive usual care for 3 weeks. Caregivers may assist patients in the use of the computer based symptoms reporting system.

After completing study intervention, participants are followed up for 30 days.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
20
Inclusion Criteria
  • PATIENT: Active outpatient cancer treatment (chemotherapy, immunotherapy, radiation, and hormonal therapy)
  • PATIENT: No clinical evidence of cognitive or psychological impairment.
  • PATIENT: Home internet access on computer or phone.
  • CAREGIVER: Selected family member or close friend of the cancer patient matching the patient inclusion criteria outlined above.
Exclusion Criteria
  • Inability to provide informed consent.

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
Arm II (computer-based symptom reporting, usual care)Quality-of-Life AssessmentParticipants use a computer based symptom reporting system for 3 weeks, then receive usual care for 3 weeks. Caregivers may assist patients in the use of the computer based symptoms reporting system.
Arm I (usual care, computer-based symptom reporting)Quality-of-Life AssessmentParticipants receive usual care for 3 weeks, then use a computer based symptom reporting system for 3 weeks. Caregivers may assist patients in the use of the computer based symptoms reporting system.
Arm I (usual care, computer-based symptom reporting)Best PracticeParticipants receive usual care for 3 weeks, then use a computer based symptom reporting system for 3 weeks. Caregivers may assist patients in the use of the computer based symptoms reporting system.
Arm I (usual care, computer-based symptom reporting)Questionnaire AdministrationParticipants receive usual care for 3 weeks, then use a computer based symptom reporting system for 3 weeks. Caregivers may assist patients in the use of the computer based symptoms reporting system.
Arm II (computer-based symptom reporting, usual care)Best PracticeParticipants use a computer based symptom reporting system for 3 weeks, then receive usual care for 3 weeks. Caregivers may assist patients in the use of the computer based symptoms reporting system.
Arm II (computer-based symptom reporting, usual care)Computer ApplicationParticipants use a computer based symptom reporting system for 3 weeks, then receive usual care for 3 weeks. Caregivers may assist patients in the use of the computer based symptoms reporting system.
Arm I (usual care, computer-based symptom reporting)Computer ApplicationParticipants receive usual care for 3 weeks, then use a computer based symptom reporting system for 3 weeks. Caregivers may assist patients in the use of the computer based symptoms reporting system.
Arm II (computer-based symptom reporting, usual care)Questionnaire AdministrationParticipants use a computer based symptom reporting system for 3 weeks, then receive usual care for 3 weeks. Caregivers may assist patients in the use of the computer based symptoms reporting system.
Primary Outcome Measures
NameTimeMethod
Effectiveness of the computer-based symptom reporting system (FACT-G)6 weeks

Evaluated using the quality of life outcome Functional Assessment of Cancer Therapy - General (FACT-G) scale. For the FACT-G, the 4 repeated measures (excluding the baseline) will be analyzed in linear mixed effects models with the random effect of user group (patient and caregiver) and fixed effect of period, sequence. The model will be used to compute the 90% confidence intervals for the mean FACT-G on usual care and on the digital system.

Usability of the computer-based symptom reporting system6 weeks

Assessed with the System Usability Scale (SUS). The SUS is a 10-item 5-point Likert scale usability measure, scored from 0 (least usable) to 100 (most usable). The mean SUS scores (only during the active cancer treatment) will be computed with the corresponding 90% confidence intervals.

Patient-deemed usefulness of computer-based symptom reporting system6 weeks

Assessed with the Perceived System Usefulness (PSU) scale. The mean PSU scores (only during the active cancer treatment) will be computed with the corresponding 90% confidence intervals.

Effectiveness of the computer-based symptom reporting system (CDSES-R)6 weeks

Evaluated using the self-efficacy Chronic Disease Self-Efficacy Scale, Revised (CDSES-R) scale. For the CDSES-R, the 4 repeated measures (excluding the baseline) will be analyzed in linear mixed effects models with the random effect of user group (patient and caregiver) and fixed effect of period, sequence. The model will be used to compute the 90% confidence intervals for the mean CDSES-R on usual care and on the digital system.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (2)

Thomas Jefferson University Hopsital

🇺🇸

Philadelphia, Pennsylvania, United States

Kennedy Health Systems- Cancer Center

🇺🇸

Sewell, New Jersey, United States

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