Effects of Combined Sevoflurane and Nitrous Oxide Inhalation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Pain intensity, pain bothersomeness
研究概览
简要总结
The purpose of this study is to determine the effects of combined sevoflurane and nitrous oxide inhalation on mood, psychomotor performance, and the pain response in humans.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Placebo +/- 30% Nitrous oxide
干预措施: 30% Nitrous oxide (Drug)
Placebo +/- 30% Nitrous oxide
干预措施: Placebo (Other)
Sevoflurane 0.2% +/- 30% Nitrous oxide
干预措施: 30% Nitrous oxide (Drug)
Sevoflurane 0.2% +/- 30% Nitrous oxide
干预措施: 0.2% sevoflurane (Drug)
Sevoflurane 0.4% +/- 30% Nitrous oxide
干预措施: 30% Nitrous oxide (Drug)
Sevoflurane 0.4% +/- 30% Nitrous oxide
干预措施: 0.4% Sevoflurane (Drug)
结局指标
主要结局
Pain intensity, pain bothersomeness
时间窗: During inhalation
Inhalation was for 68 min divided into 4 blocks with nitrous oxide added during either block 2 or block 4
Mood
时间窗: During inhalation
Inhalation was for 68 min divided into 4 blocks with nitrous oxide added during either block 2 or block 4
Psychomotor performance
时间窗: During inhalation
Inhalation was for 68 min divided into 4 blocks with nitrous oxide added during either block 2 or block 4
次要结局
未报告次要终点