Effects of Combined Sevoflurane and Nitrous Oxide Inhalation - 14
Not Applicable
Completed
- Conditions
- Opioid-Related DisordersSubstance-Related Disorders
- Interventions
- Registration Number
- NCT00000262
- Lead Sponsor
- University of Chicago
- Brief Summary
The purpose of this study is to determine the effects of combined sevoflurane and nitrous oxide inhalation on mood, psychomotor performance, and the pain response in humans.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
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Exclusion Criteria
Not provided
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Placebo +/- 30% Nitrous oxide 30% Nitrous oxide - Placebo +/- 30% Nitrous oxide Placebo - Sevoflurane 0.2% +/- 30% Nitrous oxide 30% Nitrous oxide - Sevoflurane 0.2% +/- 30% Nitrous oxide 0.2% sevoflurane - Sevoflurane 0.4% +/- 30% Nitrous oxide 30% Nitrous oxide - Sevoflurane 0.4% +/- 30% Nitrous oxide 0.4% Sevoflurane -
- Primary Outcome Measures
Name Time Method Pain intensity, pain bothersomeness During inhalation Inhalation was for 68 min divided into 4 blocks with nitrous oxide added during either block 2 or block 4
Mood During inhalation Inhalation was for 68 min divided into 4 blocks with nitrous oxide added during either block 2 or block 4
Psychomotor performance During inhalation Inhalation was for 68 min divided into 4 blocks with nitrous oxide added during either block 2 or block 4
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of Chicago, Anesthesia & Critical Care
🇺🇸Chicago, Illinois, United States