Effects of Combined Alcohol and Nitrous Oxide Intake - 15

Not Applicable

Completed

• Conditions: Opioid-Related Disorders; Substance-Related Disorders
• Interventions: Drug: 30% Nitrous oxide; Other: 0 g/Kg ethanol; Other: 0.25 g/Kg ethanol; Other: 0.5 g/KG ethanol

• Registration Number: NCT00000263
• Lead Sponsor: University of Chicago

Brief Summary

The purpose of this study is to determine the effects of combined alcohol and nitrous oxide intake on mood, psychomotor performance, and the pain response in healthy volunteers.

Detailed Description

Not available

Study Timeline

• Study Start: 1997-01
• Primary Completion: 1998-10
• Study Completion: 1998-10
• Study First Submitted: 1999-09-20
• Study First Submitted QC: 1999-09-20
• Study First Posted: 1999-09-21
• Status Verified: 2015-05
• Last Update Submitted: 2015-05-26
• Last Update Posted: 2015-05-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 11

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
0 g/Kg ethanol +/- 30% nitrous oxide	30% Nitrous oxide	-
0 g/Kg ethanol +/- 30% nitrous oxide	0 g/Kg ethanol	-
0.25 g/Kg ethanol +/- 30% nitrous oxide	30% Nitrous oxide	-
0.25 g/Kg ethanol +/- 30% nitrous oxide	0.25 g/Kg ethanol	-
0.5 g/Kg ethanol +/- 30% nitrous oxide	30% Nitrous oxide	-
0.5 g/Kg ethanol +/- 30% nitrous oxide	0.5 g/KG ethanol	-

Primary Outcome Measures

Name	Time	Method
Mood	Post inhalation
Psychomotor performance	Post inhalation
Pain intensity, pain bothersomeness	Post inhalation
Cognitive performance	Post inhalation

Trial Locations

Locations (1)

University of Chicago, Anesthesia & Critical Care; 🇺🇸 Chicago, Illinois, United States