The effect of Gaviscon on acid reflux episodes and on the position of the gastric acid pocket: A Scintigraphic study

Completed

• Conditions: Gastroesophageal reflux disease; heartburn; 10017977

• Registration Number: NL-OMON35613
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 32

Inclusion Criteria

- GERD confirmed by pH-impedance (ph<4 in >4,5 % of time or positive symptom association), or in patients with reflux esophagitis
- Written informed consent
- 18-75 years;

Exclusion Criteria

- surgery of the gastrointestinal tract other then appendectomy
- inability to stop the use of proton pump inhibitors for one week;
- participation in another study with exposure to radiation within the last year;
- long segment of Barrett*s epithelium;

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>- Acid reflux episodes</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Postprandial esophageal acid exposure<br /><br>- The rate of acid versus non acid reflux events<br /><br>- Non acid reflux events<br /><br>- The position of the acid pocket, relative to the crural diaphragm</p><br>