the Effect of Opioid-free General Anesthesia on the Recovery Quality After Gynecological Laparoscopy
Overview
- Phase
- Not Applicable
- Intervention
- Dexmedetomidine Hydrochloride
- Conditions
- Gynecologic Disease
- Sponsor
- The Catholic University of Korea
- Enrollment
- 78
- Locations
- 1
- Primary Endpoint
- the quality of recovery
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
This study is performed to investigate the effect of opioid-free general anesthesia on the recovery quality after gynecological laparoscopy.
Detailed Description
The quality of recovery after the surgery is assessed using the QoR 40. In addition, the various kinds of cytokine are assessed for the ancillary study.
Investigators
Young Eun Moon
associate professor
The Catholic University of Korea
Eligibility Criteria
Inclusion Criteria
- •patient scheduled for gynecological laparoscopic surgery
Exclusion Criteria
- •refusal to participate in this study
- •emergent surgery
- •chronic pain requiring for pain killer
- •psychiatric disease
- •preoperative bradycardia or hypotension
- •allergy or history of the adverse effect to study drug
- •pregnancy or lactation
Arms & Interventions
opioid-free anesthesia
The study group receives the dexmedetomidine and lidocaine infusion with general anesthesia for gynecological laparoscopy.
Intervention: Dexmedetomidine Hydrochloride
opioid-free anesthesia
The study group receives the dexmedetomidine and lidocaine infusion with general anesthesia for gynecological laparoscopy.
Intervention: Lidocaine Hydrochloride
opioid anesthesia
The control group receives the remifentanil infusion with general anesthesia for gynecological laparoscopy.
Intervention: Remifentanil Hydrochloride
Outcomes
Primary Outcomes
the quality of recovery
Time Frame: at 24 hour after the completion of surgery
The quality of recovery is assessed using questionnaire. This questionnaire includes 40 items. The score range is from 40 to 200. The higher score means the better quality of recovery after surgery.
Secondary Outcomes
- cytokine(during surgery)