the Effect of Opioid-free General Anesthesia on the Recovery Quality After Gynecological Laparoscopy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 78
- 试验地点
- 1
- 主要终点
- the quality of recovery
研究概览
简要总结
This study is performed to investigate the effect of opioid-free general anesthesia on the recovery quality after gynecological laparoscopy.
详细描述
The quality of recovery after the surgery is assessed using the QoR 40. In addition, the various kinds of cytokine are assessed for the ancillary study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •patient scheduled for gynecological laparoscopic surgery
排除标准
- •refusal to participate in this study
- •emergent surgery
- •chronic pain requiring for pain killer
- •psychiatric disease
- •preoperative bradycardia or hypotension
- •allergy or history of the adverse effect to study drug
- •pregnancy or lactation
研究组 & 干预措施
opioid-free anesthesia
The study group receives the dexmedetomidine and lidocaine infusion with general anesthesia for gynecological laparoscopy.
干预措施: Dexmedetomidine Hydrochloride (Drug)
opioid-free anesthesia
The study group receives the dexmedetomidine and lidocaine infusion with general anesthesia for gynecological laparoscopy.
干预措施: Lidocaine Hydrochloride (Drug)
opioid anesthesia
The control group receives the remifentanil infusion with general anesthesia for gynecological laparoscopy.
干预措施: Remifentanil Hydrochloride (Drug)
结局指标
主要结局
the quality of recovery
时间窗: at 24 hour after the completion of surgery
The quality of recovery is assessed using questionnaire. This questionnaire includes 40 items. The score range is from 40 to 200. The higher score means the better quality of recovery after surgery.
次要结局
- cytokine(during surgery)
研究者
Young Eun Moon
associate professor
The Catholic University of Korea