Injectable Lidocaine Versus Lidocaine/Tetracaine Patch for the Incision and Drainage of Skin Abscesses

Early Phase 1

Completed

• Conditions: Cutaneous Abscess; Pain
• Interventions: Drug: 1% lidocaine; Drug: Lidocaine/tetracaine patch

• Registration Number: NCT02066818
• Lead Sponsor: East Carolina University

Brief Summary

Local anesthesia used for incision and drainage of abscesses is known to be painful.

We studied the analgesia provided by a lidocaine/tetracaine patch compared to injectable lidocaine during incision and drainage (I\&D) of skin abscesses.

Local injection of lidocaine provided similar analgesia compared to the lidocaine/tetracaine patch during I\&D of skin abscesses in the Emergency Department. Pain at presentation and following the procedure was similar in both groups.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-01
• Primary Completion: 2010-01
• Study Completion: 2010-01
• Study First Submitted: 2013-11-18
• Status Verified: 2014-02
• Study First Submitted QC: 2014-02-18
• Last Update Submitted: 2014-02-18
• Study First Posted: 2014-02-20
• Last Update Posted: 2014-02-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Age>18 years
• Skin abscess in need of incision and drainage (judged by treating physician)

Exclusion Criteria

• Allergy to lidocaine or tetracaine
• Non-intact skin
• Unable/unwilling to provide informed consent

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Lidocaine Injection	1% lidocaine	Incision and drainage performed after patient received placebo patch with injection of 1% lidocaine into the site of the abscess.
Lidocaine/tetracaine patch	Lidocaine/tetracaine patch	Incision and drainage performed after patient received active lidocaine/tetracaine patch and injection of 10cc of saline into site of abscess

Primary Outcome Measures

Name	Time	Method
Change in VAS pain score over time	Immediately prior to starting I&D (Time 0); 2-5 minutes after start of I&D (Time 1); within 1 minute of completion of I&D (Time 2)	VAS measured at each of the 3 time points noted above.