Magnetic stimulation of cerebellum (a part of brain) in schizophrenia patients as a form of treatment
Not Applicable
Completed
- Conditions
- Health Condition 1: null- Schizophrenia
- Registration Number
- CTRI/2015/03/005600
- Lead Sponsor
- Central Institute of Psychiatry
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
1. Diagnosis of Schizophrenia (F20.0-F20.9) according to
ICD-10-DCR
2. Patients on a stable dose of antipsychotic medication
3. Patients of either sex aged between 18-60 years.
4. Right handed, normotensive patients.
5. Patients giving written informed consent.
6. Screened eligible for rTMS.
Exclusion Criteria
1. Current neurological or any comorbid psychiatric disorders.
2. History of substance abuse (Except nicotine and caffeine) in the
past one month.
3. History of epilepsy, significant head injury or any neurosurgical
procedure.
4. Subjects with cardiac pacemakers or other metal parts in the
body.
5. Subjects who have received ECT in past 6 months.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Composite positive and negative symptoms assessed using the Positive and Negative Syndrome Scale (PANSS)Timepoint: Baseline, after last session and at 4 weeks (2 weeks post-rTMS)
- Secondary Outcome Measures
Name Time Method Depressive symptoms using the Calgary Depression Scale for Schizophrenia (CDSS) and extrapyramidal side effects using Simpson-Angus Extrapyramidal Side Effects ScaleTimepoint: Baseline, after last session and at 4 weeks (2 weeks post-rTMS)