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Clinical Trials/NCT00208858
NCT00208858
Completed
Phase 2

Nicotine Craving: Neural Correlates of Treatment Effect - A Pilot Study

Emory University1 site in 1 countryDecember 2004
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ConditionsTobacco Use Disorder
DrugsTopiramate

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Tobacco Use Disorder
Sponsor
Emory University
Locations
1
Status
Completed
Last Updated
11 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The purpose of this study is to gather pilot data to determine feasibility of and guide the development of a larger clinical trial investigating the effects of topiramate as an adjunct to nicotine replacement therapy and behavioral counseling in smoking cessation treatment. It is hypothesized that topiramate will decrease nicotine craving and result in improved outcomes for smoking cessation.

Registry
clinicaltrials.gov
Start Date
December 2004
End Date
December 2006
Last Updated
11 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Male

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Karen Drexler

Asc Professor/Director, Substance Abuse Treatment

Emory University

Eligibility Criteria

Inclusion Criteria

  • •Male, between ages of 18-55
  • •Meets DSM-IV criteria for nicotine dependence
  • •Smoke at least 20 cigarettes per day
  • •Motivated to quit smoking

Exclusion Criteria

  • •Serious or unstable medical conditions
  • •Current psychiatric disorder requiring medication or treatment
  • •Taking medication that create risk of interaction with study drug
  • •Current participation in another smoking cessation treatment

Outcomes

Primary Outcomes

Not specified

Study Sites (1)

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