Effect of exogenous albumin on the incidence of postoperative acute kidney injury in patients with hypoalbuminemia undergoing off-pump coronary bypass surgery
Not Applicable
Recruiting
- Conditions
- Diseases of the circulatory system
- Registration Number
- KCT0000210
- Lead Sponsor
- Asan Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 220
Inclusion Criteria
patients above 20 years of age and of either sex undergoing elective off pump coronary artery bypass surgery and showing an serum albumin level of < 4.0 g/dL the day before surgery
Exclusion Criteria
1) emergency
2) patients with a history of allergic reactions to human albumin
3) patients with preoperative creatinine level = 1.5 mg/dl, or requiring dialysis
4) patients with a preoperative inotrope, intraaortic balloon pump, or ventricular assist device support
5) left ventricular ejection fraction (LVEF) = 40%
6) patients undergoing concomitant valvular or aortic surgery
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of acute kidney injury after surgery
- Secondary Outcome Measures
Name Time Method time to eligibility for discharge from intensive care unit;time to eligibility for discharge from hospital;incidence of renal replacement therapy after surgery;death from any cause within 30 days of surgery