Effects of Electrical Stimulation applied to the skin on the decrease in the blood of inflammatory cells in patients with Breast Cancer

Phase 2

Recruiting

• Conditions: breast cancer; D12.644.276.374; D23.469

• Registration Number: RBR-10jbwh47
• Lead Sponsor: Faculdade de Medicina do ABC (FMABC)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-03-25
• Study Completion: 2021-09-30
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Woman over 18 years; primary diagnosis confirmed by immunohistochemistry and biopsy; not having started chemotherapy.

Exclusion Criteria

Metastatic disease or bilateral breast cancer; any other malignancy in the past 5 years; biological therapy for any indication; rheumatic ot orthopedic disease; physical therapy with indication of pain or inflammation; uncontrolled cardiovascular or endocrine disease; active infection; recent major surgery

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary endpoint 1: Analyze the reduction in blood concentration of pro-inflammatory cytokines using the ELISA method.;Primary endpoint 2: Analyze the effect size according to each type of proinflammatory cytokine (interleukin 8, interleukin 6 interleukin 2, interleukin 1 and TNF alpha).

Secondary Outcome Measures

Name	Time	Method
Secondary endpoint 1: Analyze the size of the blood reduction effect of proinflammatory cytokines according to breast cancer immunohistochemistry;Secondary endpoint 2: Analyze the reduction of pro-inflammatory cytokines in urine;Secondary endpoint 3: Compare the blood reduction of pro-inflammatory cytokines with the reduction of cytokines in urine.