Circadian Rhythms and Light in Severely Brain-Injured Patients
Not Applicable
- Conditions
- G93.80R40Somnolence, stupor and coma
- Registration Number
- DRKS00016041
- Lead Sponsor
- niversität Salzburg, Zentrum für kognitive Neurowissenschaften
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 19
Inclusion Criteria
We will include patients with an apallic syndrome (unresponsive wakefulness syndrome, UWS, persistent vegetative state, PVS), as well as patients in a minimally conscious state (MCS).
Exclusion Criteria
The only exclusion criterion are strong vegetative reactions (dysautonomy) and/or motor agitation due to the study protocol, which renders data collection impossible or insensible. The decision regarding the exclusion of a patient is up to the local medical study leader. The local medical study leaders assign the suitable patients to the study following an extensive evaluation of their clinical state, e.g. regarding infections. Information regarding the medication will be collected, but is not defined as an exclusion criterion.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Coma Recovery Scale-Revised scores (best score out of two assessments on days 6 and 7 of the protocol), daily variations in body temperature, daily variations in ecg-derived measures
- Secondary Outcome Measures
Name Time Method