Effect of biphosphonates on teleangiectasia in irradiated breast cancer patients
- Conditions
- biphosphonates and telangiectasia in irradiated breast cancer patients.1000629110047043
- Registration Number
- NL-OMON36371
- Lead Sponsor
- ederlands Kanker Instituut
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
radiotherapie on breast > 6 months ago
will receice biphosphonate
age ><=18 years
Exclusion Criteria
breast radiotherapy < 6 months ago
use of anti-coagulants
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>To determine the effects of biphosphonates on radiation induced microvascular<br /><br>damage by comparison of biopsy samples of skin prior to and 4 months after<br /><br>treatment with a biphosphonate. </p><br>
- Secondary Outcome Measures
Name Time Method <p>To determine the effects of biphosphonates on radiation induced<br /><br>micro-lymphovascular damage by comparison of biopsy samples of skin prior to<br /><br>and after treatment with a biphosphonate.</p><br>