Treating Psychosocial and Neural Consequences of Childhood Interpersonal Violence in Adults

Not Applicable

Conditions: F43.1
F60.31
Post-traumatic stress disorder

Registration Number: DRKS00005578

Lead Sponsor: Zentralinstitut für Seelische GesundheitKlinik für Psychosomatik und Psychotherapeutische Medizin

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Female

Target Recruitment: 180

Inclusion Criteria

PTSD after childhood sexual or physical abuse before the age of 18 years, sexual or physical assault must be the index trauma, at least 3 criteria of BPD (including criterion 6: affective instability), commitment and possibilty to attend weekly therapy sessions for one year; no planned absence for more than 4 weeks in this period, participant has the ability to understand character and consequences of the study, informed consent

Exclusion Criteria

Lifetime diagnosis of schizophrenia, lifetime diagnosis of bipolar I disorder, mental retardation, severe psychopathology which needs to be treated immediately in another setting (e. g. BMI < 16), medical conditions making exposure based treatment impossible, current alcohol - or drug addiction,
suicide attempt within the last 2 months, inpatient treatment planned, instability of the current life conditions (e.g. homelessness, ognoing contact with offender), pregnancy, 1 year DBT-PTSD or CPT-C treatment before inclusion

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of Posttraumatic Stress Disorder<br>Assessment: Clinician Administered PTSD Scale (CAPS, Blake et al. 1995)<br>Assessment points: <br>Baseline<br>3 months after baseline<br>6 months after baseline<br>9 months after baseline<br>12 months after baseline (end of the study)<br>3 months follow-up

Secondary Outcome Measures

Name	Time	Method
Symptom-severity of borderline personality disorder <br>Assessment: Borderline Symptom List (BSL-23, Bohus et al. 2009)<br>Assessment points: <br>Baseline<br>3 months after baseline<br>6 months after baseline<br>9 months after baseline<br>12 months after baseline (end of the study)<br>3 months follow-up