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A multicenter clinical study of Ba qi ling mao formulation in the treatment of BCLC B / C stage of primary liver cancer

Phase 1
Conditions
primary liver cancer
Registration Number
ITMCTR2000003705
Lead Sponsor
Shuguang Hospial Affiliated to Shanghai University of TCM
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

1. patients with primary liver cancer after radical resection (BCLC stage B, stage C);
2. aged 18 to 70 years;
3. The patients had not received systematic treatment before, including molecular targeted drug therapy, systemic chemotherapy, immunotherapy, etc;
4. Patients who are unable or unwilling to accept surgery or have disease progression after local treatment and cannot be operated again;
5. willing to accept Chinese medicine and/or integrated Chinese and western medicine treatment;
6. sign informed consent.

Exclusion Criteria

1. metastatic liver cancer patients, or concurrent with other cancer patients;
2. Patients with refractory ascites, hepatic encephalopathy, hepatorenal syndrome and other serious complications;
3. accompanied by heart, kidney, lung, endocrine, blood, metabolism and gastrointestinal tract serious primary disease; Or mentally ill;
4. legally disabled persons, pregnant women or nursing women;
5. allergy or multiple drug allergy patients;
6. Currently participating in other clinical trials.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1 year Survival period;
Secondary Outcome Measures
NameTimeMethod
objective response rate;PIVKA-II;Child-pugh grading;Abdominal ultrasound;disease control rate;liver function;MRI;AFP;Quality of Life Scale;
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