A study based on feeding in babies with abnormal doppler of umblical cord

Not Applicable

Completed

• Conditions: Health Condition 1: P026- Newborn affected by other and unspecified conditions of umbilical cord

• Registration Number: CTRI/2019/03/017899
• Lead Sponsor: Dept of Neonatology

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2020-11-30
• Last Update Posted: 17 October 2022

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 87

Inclusion Criteria

1. All preterm babies described as newborns between 28 to 34 completed weeks of gestation born to mothers with absent/reversed end diastolic flow in umbilical artery doppler flow velocimetry admitted to Nursery and NN ward of Lady Hardinge medical college, New Delhi during the study period

2. Babies who are growth restricted (small for gestational age babies defined as birth weight less than 10th centile according to Fentonââ?¬•s chart)

3. Hemodynamically stable prior to randomization

4. Babies whose parents have given an informed consent

Exclusion Criteria

Any major congenital anomalies

Antenatally diagnosed gastrointestinal problems

Babies with evidence of birth asphyxia (Apgar score <4 at 5 mins)

Abdominal distension prior to randomization

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the time taken to reach full feeds in small for gestational age babies with gestational age between 28 to 34 completed weeks born to mothers with absent/reversed end diastolic umbilical doppler flow velocity randomized based on timing of initiation of feedsTimepoint: To compare the time taken to reach full feeds in small for gestational age babies with gestational age between 28 to 34 completed weeks born to mothers with absent/reversed end diastolic umbilical doppler flow velocity randomized based on timing of initiation of feeds

Secondary Outcome Measures

Name	Time	Method
To compare the outcome in terms of - Feed Intolerance and Necrotizing Enterocolitis, Duration of hospital stay, Weight gain and anthropometry during the hospital stay, Intravenous fluid related risks and complications, Incidence of sepsis both clinical sepsis and culture proven sepsis, All cause mortalityTimepoint: From admission till discharge of the neonate from Neonatal ward or Nursery