Management of gum recession using two types of membranes derived from blood
- Conditions
- Gingival recession,
- Registration Number
- CTRI/2022/04/042040
- Lead Sponsor
- Kavitha Sridhar
- Brief Summary
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|Gingival recession is defined as the apical displacement of gingival margin to the cemento enamel junction (CEJ) exposing the root surface (**Gustavo et al 2021** ). The causative factors include faulty tooth brushing, underlying periodontal disease, malaligned tooth, high frenal attachment causing marginal gingival pull, subsequently leading to the exposure of root causing esthetic concerns, hypersensitivity, plaque retention and caries to the patients.
Platelet concentrates have been widely utilized in field of periodontology and oral implantology, owing to their ability to rapidly stimulate vascularization of tissues (**Miron et al., 2017**). The rationale for utilising platelet concentrates is that these are the primary cells involved in wound healing, and they initiate the coagulation cascade, resulting in the formation of a fibrin meshwork that works as a provisional matrix, maintaining the space for regeneration.
The preparation of platelets concentrates is based on the principle of the centrifugation process to separate particles of different densities. The potential benefits of platelet rich fibrin(PRF) obtained by horizontal method of centrifugation, in management of gingival recession has not yet been clearly established . Therefore, we propose this research to evaluate the clinical efficacy of H-PRF in management of Cairo’s RT1 and RT2 recessions in maxillary anteriors and premolars along with coronally advanced flap (CAF) and to compare the outcomes with that of PRF obtained by angle spin protocol.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 44
- Systemically healthy subjects with an age range of 18-65 years.
- Individuals diagnosed with recession defects in maxillary anteriors and premolars (Cairo’s RT1 & RT2 class of recession) 3.
- Sites with minimum depth of recession ≥2mm.
- Isolated or multiple adjoining recession involving ≤3 teeth.
- Sites with probing pocket depth ≥4mm.
- Teeth with mobility and/or associated with trauma from occlusion.
- Sites with dental caries and prosthetic restorations.
- Patients who exhibit unacceptable oral hygiene compliance during/or after phase Ι therapy.
- Pregnant and lactating women.
- Patients with known platelet disorders or using any medication that are known to interfere with platelet function.
- Patients with systemic conditions or disease influencing the course of periodontal disease and therapy.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the following parameters between the study groups Baseline | 3 Months | 6 Months 1. Recession height Baseline | 3 Months | 6 Months 2. Root coverage percentage Baseline | 3 Months | 6 Months
- Secondary Outcome Measures
Name Time Method To compare the following parameters between the study groups 1. Width of keratinized gingiva
Trial Locations
- Locations (1)
SRM dental college
🇮🇳Chennai, TAMIL NADU, India
SRM dental college🇮🇳Chennai, TAMIL NADU, IndiaKavitha sridharPrincipal investigator7708468555kavithashobana123@gmail.com