Analgesic effect of Penthrox spray in patients with upper or lower limb fracture

Phase 3

Recruiting

• Conditions: Analgesics.; Opioids and related analgesics; Y45.0

• Registration Number: IRCT20230302057587N1
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 1 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

Patients with upper or lower fracture
Age between 20 to 55
Informed consent to participation in the study

Exclusion Criteria

Impaired level of consciousness (Glasgow coma score less than 15)
Hemodynamic disturbance during use (systolic blood pressure less than 90 mmHg, peripheral rate less than 60 beats per minute, breathing rate less than 8 per minute, blood oxygen saturation less than 90%
Use of substances, alcohol, sedatives or pain relievers in the past 48 hours
History of taking Monoamine Oxidase Inhibitors, Tricyclic Antidepressants, Serotonin Receptors Reuptake Inhibitors, Phenothiazines, and sleeping pills
Suffering from chronic diseases such as congenital or acquired heart diseases, chronic liver failure, bile duct diseases, kidney failure and chronic lung disease according to history and clinical examination.
Allergy to Morphine or Penthrox
Weight more than 100 kg
Lack of informed consent
Patient non-cooperation

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain number in the Visual Analogue Scale (VAS). Timepoint: 10, 20, 30, 60 minutes after receiving the medicine. Method of measurement: The Visual Analogue Scale (VAS).