To evaluate and compare the effects of injectable platelet-rich fibrin (i-PRF) which is a third generation platelet concentrate and micro-osteoperforation (MOP) also known as flapless bone puncturing on the rate of canine movement during retraction in patients requiring premolar extractions.
- Conditions
- Health Condition 1: K039- Disease of hard tissues of teeth,unspecified
- Registration Number
- CTRI/2022/12/048404
- Lead Sponsor
- KUSHAL TAORI
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1. Patients age varying from 15 â?? 30 years having class 2 division 1 and bimaxillary
protrusion that requires removal of both maxillary first premolars.
2. Patients with average growth pattern.
3. Patients with no systemic conditions and diseases.
4. Patients with fully erupted maxillary canine.
5. Patients with healthy periodontal parameters having no clinical attachment loss or PPD
more than 2-3 mm.
6. Patients indicated for fixed orthodontic therapy.
1. Patients with horizontal and vertical growth pattern.
2. Patients with developmental and congenital syndromes.
3. Patients with any systemic diseases like clotting disorders and conditions like pregnancy,
anticoagulant therapy.
4. Patients above the age of 30 years.
5. Patients with deleterious habits like smoking are the subjects to be excluded.
6. Patients undergoing removal or myofunctional orthodontic treatment.
7. Patients on medication that decease orthodontic tooth movement like NSAIDS(Ibuprofen,
aspirin, aceclofenac, diclofenac), bisphosphonates, hormonal replacement therapies.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Rate of canine retraction.Timepoint: At T1 T2 T3 T4 <br/ ><br>T1 - one week post extraction <br/ ><br>T2 - four weeks post extraction <br/ ><br>T3 - 8 weeks post extraction <br/ ><br>T4 - 12 weeks post extraction
- Secondary Outcome Measures
Name Time Method Pain assessment in both the groups.Timepoint: at T1 T2 T3 T4 where, <br/ ><br>T1 - one week post extraction <br/ ><br>T2 - four weeks post extraction <br/ ><br>T3 - 8 weeks post extraction <br/ ><br>T4 - 12 weeks post extractioon