Effects of Neutrophil/Lymphocyte, Platelet/Lymphocyte, CRP/Albumin and Lactate on Mortality in Trauma Patients Admitted to Intensive Care

Completed

• Conditions: Intensive Care

• Registration Number: NCT06667310
• Lead Sponsor: Harran University

Brief Summary

Intensive care units are medical units where patients are closely monitored 24 hours a day due to critical health problems that threaten their lives and where rapid interventions are made when necessary. The clinical conditions of patients in these units can change rapidly. There are many studies in the literature indicating that inflammation indicators such as Neutrophil/Lymphocyte, Platelet/Lymphocyte and C-Reactive Protein/Albumin ratios and blood gas values such as Lactate and Base Deficit are simple, cheap and rapid biomarkers that can provide an early idea about the clinical course of patients.

Detailed Description

Intensive care units are medical units where patients are closely monitored 24 hours a day due to critical health problems that threaten their lives and where rapid interventions are made when necessary. The clinical conditions of patients in these units can change rapidly. There are many studies in the literature indicating that inflammation indicators such as Neutrophil/Lymphocyte, Platelet/Lymphocyte and C-Reactive Protein/Albumin ratios and blood gas values such as Lactate and Base Deficit are simple, cheap and rapid biomarkers that can provide an early idea about the clinical course of patients. The researchers aimed to evaluate the relationship between Neutrophil/Lymphocyte, Platelet/Lymphocyte and C-Reactive Protein/Albumin ratios and biomarkers such as Lactate and Base Deficit with the clinical course and survival of trauma patients admitted to the ICU and to see the compatibility of our data with the existing literature.

Study Timeline

• Study First Submitted: 2024-10-25
• Study First Submitted QC: 2024-10-30
• Study First Posted: 2024-10-31
• Study Start: 2024-11-05
• Primary Completion: 2025-01-10
• Status Verified: 2025-05
• Last Update Submitted: 2025-05-14
• Study Completion: 2025-05-15
• Last Update Posted: 2025-05-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• 1. All trauma patients admitted to our general intensive care unit

Exclusion Criteria

• 1. Patients whose follow-up and treatment started and completed in the services.

2. Patients whose data is missing or whose data cannot be accessed.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary outcome	one day	1. LACTATE LEVELS RATİO MEASUREMENT

Secondary Outcome Measures

Name	Time	Method
seconary outcome	one day	The effect of these measurements on mortality

Trial Locations

Locations (1)

Veli Fahri Pehlivan; 🇹🇷 Karaköprü, Şanliurfa, Turkey