Evaluation of the therapeutic effect of crocin along with standard regimes in colorectal cancer

Phase 3

Recruiting

• Conditions: colorectal cancer.; Malignant neoplasm of rectosigmoid junction

• Registration Number: IRCT20131017015044N2
• Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 February 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Colorectal cancer patients with lung or liver metastasis or both that is measurable
Colorectal cancer patients who have not received any chemotherapy for metastasis

Exclusion Criteria

History of any allergy to saffron or its products

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Overall survival. Timepoint: One year after the treatment is completed. Method of measurement: Patient follow-up.

Secondary Outcome Measures

Name	Time	Method
Progression-free survival. Timepoint: During treatment and after it every 3 months. Method of measurement: criteria of Response evaluation criteria in solid tumors.;Anemia. Timepoint: Before each session of monthly chemotherapy. Method of measurement: laboratory assessment of complete blood count.;Neutropenia. Timepoint: Before each session of monthly chemotherapy. Method of measurement: laboratory assessment of complete blood count.;Thrombocytopenia. Timepoint: Before each session of monthly chemotherapy. Method of measurement: laboratory assessment of complete blood count.;Kidney function. Timepoint: Before each session of monthly chemotherapy. Method of measurement: laboratory assessment of BUN and creatinine.;Liver function. Timepoint: Before each session of monthly chemotherapy. Method of measurement: laboratory assessment of SGOT and SGPT.