Randomised control trial for comparison of 12hours v/s 24 hours post-partum maintenance therapy of magnesium sulphate in severe pre- eclampsia and eclampsia patients’
试验速览
- 阶段
- Phase 3 4
- 状态
- 招募中
- 入组人数
- 198
- 试验地点
- 1
- 主要终点
- To determine the recurrence of convlsions in patients receiving 12hrs/24hrs maintenance dose of magnesium sulphate
研究概览
简要总结
Magnesium sulphate is a drug of choice for severe pre eclampsia and eclampasia patients. As per standard protocol this drug is given as an loading dose 4gm inta venous followed by maintenance dose for 24 hours ,but this standard protocol is made by western country and we are also followed it. As our Indian women having weight less than western country so the need of dose is lesser in India. Many studies are done in India and are found significant.In this study loading dose of magnesium 4gm intavenous followed by maintennace dose 1gm per hour intravenous for a duration of 12hours instant of 24hrs by randomised control trial.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- Female
入选标准
- •Women with severe pre-eclapsia and eclampsia admitted to OBGY department PSMC,karmsad.
排除标准
- •Status eclampicus Renal compromise Patient recieve other anti convulsant except magnesium sulphate.
结局指标
主要结局
To determine the recurrence of convlsions in patients receiving 12hrs/24hrs maintenance dose of magnesium sulphate
时间窗: To determine the recurrence of convlsions in patients receiving 12hrs/24hrs maintenance dose of magnesium sulphate
次要结局
- maternal morbidity(Respiratory failure,ICU admission,total hospital stay,hospital acquired infection.)
研究者
sunita pandya
PSMC karmsad anand