Dynamic whole-body [18F]FDG-PET/CT for patients with lung cancer
Not Applicable
- Conditions
- C34Malignant neoplasm of bronchus and lung
- Registration Number
- DRKS00017717
- Lead Sponsor
- niversitätsklinikum Tübingen, Nuklearmedizin
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 38
Inclusion Criteria
• Patients with clinical suspicion or histologically confirmed NSCLC ((non small cell lung carcinoma)
• Justifying clinical indication for a [18F]FDG-PET investigation
• Patients who tolerate 1 h measurement time in the PET/CT scanner
• Age =18 years
• Written consent of the patient
Exclusion Criteria
• pregnant and nursing women
• Patients with claustrophobia
• Patients with back pain problems / pain that may not tolerate a one-hour measurement period
• Exclusion criteria according to German StrlSchV
• Limited ability to consent of the patient
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Collection of dynamic PET parameters (Ki, DV, K1 and Vb) from the primary tumor, lymph node regions and distant metastases of NSCLC patients and their correlation with histopathological findings (gold standard) of the same regions (feasibility study). Histopathological analyzes are performed on biopsies or surgical material collected as part of the routine care of patients.
- Secondary Outcome Measures
Name Time Method • Differentiation of inflammatory and tumor-associated tissue changes by means of suitable dynamic PET parameters,<br>• Identification of malignant lymph nodes using dynamic PET parameters,<br>• Establishment of the workflow for a dynamic wb-PET/CT in NSCLC patients.<br>(Endpoint of the study: PET/CT datasets and immunhistol. analyses of tissue probes (taken as part of standard of care) are available)