Efficacy of palonosetoron compared with granisetron for prevention of chemotherapy-induced nausea and vomiting (CINV) using MASCC antiemetic tool
Not Applicable
- Conditions
- ung cancer, Colon cancer, Breast cancer
- Registration Number
- JPRN-UMIN000005268
- Lead Sponsor
- Shimane University Faculty of Medicine Division of Clinical Oncology and Respiratory Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Not provided
Exclusion Criteria
1)Patient with dementia 2)Concurrent brain radiotherapy 3)Serious infections 4)Clinical brain metastasis 5)Massive pericardial, pleural effusion, or ascites 6)Vestibular disorder 7)Clinical hypercalcaemia or hyponatremia 8)Clinical uremia 9)Ireus or sub-ireus 10)Serious clinical probrems 11)Previous drug allergy 12)Hoped to be pregnant/ nursing 13)Those judged to be not suitable by the attending physician
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Score of delayed CINV in MAT
- Secondary Outcome Measures
Name Time Method 1)Score of nausea in FLIE 2)Score of vomiting in FLIE 3)Number of delayed vomiting 4)Number of acute vomiting 5)Number of acute nausea 6)Number of acute vomiting 7)Plasma concentration of 5-HIAA, Substance P and ghrelin