Evaluation of postoperative nausea and vomiting prevention by comparing Granisetron and Palonosetron in adult patients undergoing laparoscopic surgery.
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2021/09/036824
- Lead Sponsor
- ABVIMS and Dr Ram Manohar Lohia Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients undergoing laparoscopic surgery.
ASA grade - 1 and 2 .
Exclusion Criteria
1) Patient having history of motion sickness or past history of PONV
2) Opioid dependence
3) Pregnant females
4) Patients with liver diseases
5) Patients receiving chemotherapy or radiotherapy within the past four weeks.
6) Use of antiemetic drugs within 24 hours prior to surgery.
7) Allergy to any drug used in the study.
8) Patients taking drug which increases serotonin release like selective serotonin reuptake inhibitors ( citalopram, fluoxetine, paroxetine)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of post operative nausea and vomiting in the first 24 hours following conclusion of anaesthesia <br/ ><br>Timepoint: In first 24 hours <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1) Requirement of rescue antiemetic. <br/ ><br>2) Overall satisfaction of patient with nausea and vomiting experience. <br/ ><br>3) Occurence of adverse effects like headache, dizziness, drowsiness, injection site pain or reaction etc.Timepoint: After 24 hours