Mechanisms of vitamin C in immune response, microRNA expression and telomere length
- Conditions
- Type two diabetes and non type two diabetes mellitus
- Registration Number
- TCTR20190416002
- Lead Sponsor
- Khon Kaen University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Inclusion criteria of healthy control include age between 30 and 60 years old, Non type two diabetes mellitus, normal resting EKG, lack of any chronic diseases and chronic infections such as HIV, hepatitis and TB, have no consumption any supplementary at least 3 months, lack of any regular exercise program for at least 6 months and live in Khon Kaen Province, Thailand. For T2DM, the inclusion criteria include age between 30 and 60 years old, being diagnosed as type 2 diabetes mellitus for at least 12 months, being treated with oral diabetic drugs only (no insulin injection), receiving lipid-lowing drugs or anti-hypertensive drugs, sedentary and lack of any regular exercise program for at least 6 months and living in Khon Kaen Province, Thailand.
Abnormal resting EKG, chronic diseases and chronic infections such as HIV, hepatitis and TB, have consumption any supplementary at least 3 months, have a regular exercise program for at least 6 months. For T2DM, being diagnosed as type 2 diabetes mellitus early than 12 months, being treated with insulin injection.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Telomere length 1 day Real time PCR based technique,immune response 1 day Flow cytometry,microRNA expression 1 day microarray,microRNA expression 1 day microarray
- Secondary Outcome Measures
Name Time Method Heart rate availability 5 minutes Detected by SA-3000P