The effect of vitamin C in shock
Phase 3
Recruiting
- Conditions
- Hemodynamic Shock.Shock, unspecifiedR57.9
- Registration Number
- IRCT20120216009045N5
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 42
Inclusion Criteria
Patients over 20 years old
Undergoing elective colon cancer surgery for the first time
Following the postoperative shock, they are immediately admitted to the IC
Exclusion Criteria
Sepsis before surgery
Myocardial ischemia in a recent hospitalization (positive troponin test on two time)
Acute kidney injury (creatinine increase 1.5 times the baseline creatinine level)
Immunotherapy before surgery
oxalate kidney stones
G6PD enzyme deficiency
History of rheumatic disease
History of corticosteroid use
History of rheumatic disease
Morbid obesity (BMI =40)
Simultaneous cancers in other organs
metastatic cancer
Previous colon cancer surgery
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Inflammatory factors ( IL-6, CRP, Lactate, ESR). Timepoint: At the beginning of the study and then daily for 5 days. Method of measurement: Laboratory examination of blood samples.
- Secondary Outcome Measures
Name Time Method ength of hospitalization. Timepoint: From the beginning of the study until discharge or death. Method of measurement: Daily checking of the variables by the researcher.;Duration of hospitalization in the intensive care unit. Timepoint: From the beginning of the study on a daily basis until discharge or death from the intensive care unit. Method of measurement: Number of days assessed by the researcher.