Effects of low carbohydrate availability with high protein or high fat on the response to training and performance.

Not Applicable

Completed

• Conditions: Metabolic response to training; Diet and Nutrition - Other diet and nutrition disorders; Metabolic and Endocrine - Normal metabolism and endocrine development and function

• Registration Number: ACTRN12616000433404
• Lead Sponsor: Professor John Hawley

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-04-05
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 8

Inclusion Criteria

Well trained cyclists riding more than 200 km per week.
A VO2max of > 60 ml/kg/min (this is tested in the lab via a short incremental exercise test on the bike)

Exclusion Criteria

Participants will only be excluded if they are unable to follow the dietary intervention due to an allergy or intolerance.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Substrate utilisation during prolonged, submaximal cycling using expired gas collected during exercise via a Parvomedics online gas analysis system.[Pre to post the high fat or high protein dietary intervention- They will be compared from day 1 of the high fat or high protein diet to day 6 which is 1 day following the high fat or protein diet. <br><br>Also day 5 of the carbohydrate diet will be compared to day 7 which is the large testing day when participants cycle for 100 minutes plus complete the time trial. ]

Secondary Outcome Measures

Name	Time	Method
Plasma free fatty acid response[This will be measured every 20 min during the 100 min exercise trial on day 7.];Plasma insulin response[This will be measured every 20 min during the 100 min exercise trial on day 7.];Changes in mitochondrial respiration as a consequence of the dietary intervention from muscle biopsies collected. [Pre to post the high fat or high protein dietary intervention. They will be compared from day 1 of the high fat or high protein diet to day 6 which is 1 day following the high fat or protein diet and also day 7 which is the large testing day when participants cycle for 100 minutes plus complete the time trial. ]