Effect of folic acid on red,burning and ulcerated gums
Phase 2
- Conditions
- Health Condition 1: null- Desquamative Gingivitis
- Registration Number
- CTRI/2018/03/012813
- Lead Sponsor
- Dr Saif Khan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Desquamative Gingivitis Lesion presenting as erythema, burning sensation, desquamation, ulceration of gingiva and associated oral mucosa
Exclusion Criteria
Dental plaque induced inflammatory diseases of gingiva such as gingivitis and periodontitis.
Oral Candidiasis.
Acute Herpetic gingivostomatitis.
Acute Necrotizing ulcerative gingivitis.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Healing outcome of the lesion(Complete regression/partial regression/No Regression) <br/ ><br>2.Change in the surface area of the lesion(mm2) <br/ ><br>3. Visual analog score for assessing reduction in pain perception(0 to 10 scale) <br/ ><br>Timepoint: Baseline, 2 weeks post intervention <br/ ><br>
- Secondary Outcome Measures
Name Time Method Plaque Index <br/ ><br>Gingival Index <br/ ><br>Bleeding on Probing(BOP) <br/ ><br>Salivary TNF-alpha Levels <br/ ><br> <br/ ><br>Timepoint: Baseline, 2 weeks postintervention