Clinical study of folic acid supplementation on gum health in subjects undergoing orthodontic treatment
Phase 2
- Conditions
- Health Condition 1: M263- Anomalies of tooth position of fully erupted tooth or teeth
- Registration Number
- CTRI/2024/03/064247
- Lead Sponsor
- Dr Iman Ahmad
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients having complete permanent dentition and undergoing fixed orthodontic mechanotherapy
2. Planned for premolar extractions in all 4 quadrants, followed by anterior retraction in maxillary and mandibular arches
3. Gingivitis in the anterior region after levelling and alignment stage of treatment (as per AAP 2018 classification)
Exclusion Criteria
1. Previous functional orthopaedic and/or fixed orthodontic treatment
2. Destructive periodontal disease and/or gingival recession before treatment
3. Received periodontal treatment within the previous year
4. Iron/vitamin supplement(s) within the previous 6 months
5. Systemic conditions with related medications
6. Pregnancy and lactation
7. Smoking
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Periodontal status, gingival biotype and keratinised gingival widthTimepoint: T0 baseline- after levelling and alignment of teeth, T1- after 4 months of anterior retraction, T2- after complete anterior retraction
- Secondary Outcome Measures
Name Time Method Rate of orthodontic tooth movementTimepoint: T0 baseline- after levelling and alignment of teeth, T1- after 4 months of anterior retraction, T2- after complete anterior retraction;Serum folate estimationTimepoint: T0 baseline- after levelling and alignment of teeth, T1- after 4 months of anterior retraction, T2- after complete anterior retraction