Effect of prenatal administration of folic acid on serum homocysteine and lipoprotein (a) levels in Methylenetetrahydrofolate reductase polymorphisms
Not Applicable
- Conditions
- EclampsiaPregnant Women.
- Registration Number
- IRCT2014010715903N2
- Lead Sponsor
- Drug Applied Research Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 90
Inclusion Criteria
Pregnant wemon with the average age of 20-30 years
Exclusion criteria:
Without history of heart disease; chronic hypertension; diabetes mellitus; renal disease; collagen tissue disease; history of preterm labor; abortion; drug taking calcium and ferrous sulfate; liver disease
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Homocysteine. Timepoint: before Administration and 36 weeks of gestation. Method of measurement: ELISA method using primary and secondary antibodies by ELISA reader.;Lipoprotein (a). Timepoint: before Administration and 36 weeks of gestation. Method of measurement: Nephlometric Method by Autoanalyzer.
- Secondary Outcome Measures
Name Time Method DH. Timepoint: before Administration and 36 weeks of gestation. Method of measurement: Autoanalyzer.;Urea. Timepoint: before Administration and 36 weeks of gestation. Method of measurement: Autoanalyzer.;Creatinine. Timepoint: before Administration and 36 weeks of gestation. Method of measurement: Autoanalyzer.;Platelet. Timepoint: before Administration and 36 weeks of gestation. Method of measurement: Cell counter.;Urinary creatinine. Timepoint: before Administration and 36 weeks of gestation. Method of measurement: Autoanalyzer.