euromuscular Ultrasound in Critical Illness

Completed

• Conditions: 10029317; 10002252; Intensive Care Unit - aquired weakness

• Registration Number: NL-OMON41662
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 80

Inclusion Criteria

Adult patients newly admitted to the ICU of the Academic Medical Center
- Mechanical ventilation for at least 48 hours
- Diagnosis of ICU-AW or absence of ICU-AW, according to consensus guidelines, made by physical therapist as part of routine care
- At least one arm and one leg available for testing

Exclusion Criteria

Neuromuscular disorder as reason for admission; Stroke (ischemic, hemorrhagic or subarachnoid) as reason for admission; Quadriplegia due to spinal cord syndrome in medical history or as reason for admission; Out of hospital cardiac arrest as reason for admission; Traumatic brain injury as reason for admission
Known intracerebral space occupying lesion
Poor functional status before admission (modified Rankin score 4 or 5)

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Difference in gray-scale value as measures of echointensity on standardized<br /><br>cross-sectional ultrasonographic views of five muscle groups on one side<br /><br>(biceps brachii, forearm flexor group, quadriceps femoris, tibialis anterior,<br /><br>and diaphragm) in patients with ICU-AW and patients without ICU-AW.</p><br>