euromuscular ultrasound in patients with and without ICU-acquired weakness
Completed
- Conditions
- ICU-acquired weakness, CIP, CIM, CINM, critical illness polyneuropathy, critical illness myopathy, criticall illness neuromyopathy
- Registration Number
- NL-OMON27105
- Lead Sponsor
- Academic Medical Center, AmsterdamDepartment of Intensive Care and Department of Neurology
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
Adult patients newly admitted to the ICU
-Mechanical ventilation for at least 48 hours
Exclusion Criteria
-Neuromuscular disorder as reason for admission
-Stroke (ischemic, hemorrhagic or subarachnoid) as reason for admission
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Difference in gray-scale value as measures of echointensity on standardized cross-sectional ultrasonographic views of five muscle groups in patients with ICU-AW and patients without ICU-AW.
- Secondary Outcome Measures
Name Time Method - Differences in standard deviation of the gray scale values as a measure of homogeneity of the five muscle groups between patients with ICU-AW and patients without ICU-AW.<br /><br>- Differences in cross-sectional muscle thickness as measure of muscle atrophy of the five muscle groups between patients with ICU-AW and patients without ICU-AW.<br /><br>- Differences in area and vascularity on standardized ultrasonographic views of median nerve and peroneal nerve.