Evaluation the effect of clonidine and dexmedetomidine administration on bleeding during surgery
Phase 2
- Conditions
- bleeding.
- Registration Number
- IRCT20160430027677N20
- Lead Sponsor
- Oroumia University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 64
Inclusion Criteria
Aged 20-60 years old
American Society of Anesthesiologists physical status classification I,II
General anesthesia
Exclusion Criteria
Patients with diabetes mellitus
Coagulation problems
Liver or kidney failure
Cerebrovascular disease
High blood pressure
Asthma
Chronic obstructive pulmonary disease
Severe end organ damage
Psychosis
Patients receiving antipsychotic medication
Hypersensitivity to dexmedetomidine and clonidine
Drug abusers
Use of beta blockers drugs
Heart rate less than 55 beats per minute
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Amount of bleeding. Timepoint: during surgery. Method of measurement: Measuring the amount of blood inside the suction device and the gases used.;Quality of the surgical field. Timepoint: During surgery. Method of measurement: Boezaart scale.
- Secondary Outcome Measures
Name Time Method Mean arterial pressure. Timepoint: Every 5 minutes during the surgery. Method of measurement: Non invasive pressure gauge.;Mean pulse Rate. Timepoint: Every 5 minutes during the surgery. Method of measurement: Electrocardiogram.