Post-stroke hand rehabilitation with MEG-based brain-robot interface

Not Applicable

• Conditions: eurorehabilitation of chronic stroke patients; Nervous System Diseases

• Registration Number: ISRCTN88026375
• Lead Sponsor: niversity of Ulster

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-11-24
• Last Update Posted: 16 October 2023
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1. Post-stroke volunteers aged 18 - 80 years with normal or corrected to normal vision (e.g. normal vision by using glasses)
2. 6 months - 2 years post-stroke since first episode of stroke
3. Able to follow two-part spoken or written commands
4. Have movement disability in at least one of their hands due to stroke
5. Able to get in and out of a low seat unassisted
6. Prepared to remove all body piercings

Exclusion Criteria

1. Known to have a progressive neurological condition
2. Have metal or active implants in their body (excluding dental fillings or crowns)
3. Known to suffer from claustrophobia
4. Pregnant or breast feeding
5. Gross cognitive impairment or disorientation, evidenced by a Hodgkinson mini-mental test score (HMMS) (Hodgkinson, 1972) of less than 21/30

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Functional recovery measured using the Action Research Arm Test (ARAT) and grip strength on a weekly basis during the trial period<br>2. Functional connectivity among activated brain regions will be computed using activation related MEG/EEG-EMG data on a weekly basis during the trial period

Secondary Outcome Measures

Name	Time	Method
1. Participants’ mood, motivation, and fatigue level will be continuously monitored during sessions using appropriate visual analog scales<br>2. Mood will be assessed weekly, using the Centre for Epidemiologic Studies-Depression Scale