NCT02314962终止不适用
Diagnostic and Clinical Accuracy of Integrated Magnetic Resonance Imaging and Computed Tomography Perfusion in PET/MRI in Comparison to PET/CT in Solid Tumors
适应症
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 43
- 试验地点
- 1
- 主要终点
- Measurement of blood flow, blood volume and transfer constant (Ktrans) with CT-Perfusion and PET/MR-perfusion in solid tumors.
研究概览
简要总结
Diagnostic comparison between PET/CT and PET/MRI with integrated perfusion measurement in CT and MR. Study aim is to gain knowledge about additional value of CT perfusion and MR perfusion in solid tumors concerning tumor physiology, diagnostic accuracy and possibly prognostic.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 30 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •indication as stated above
- •written informed consent
- •patients with suspected or confirmed solid malignant tumors of the neck, chest or abdomen who have an indication for a PET/CT
排除标准
- •pregnant or breast feeding women
- •non compliance of the patient to follow the study instructions (e.g. hearing problems, dementia)
- •Inclusion in another clinical trial 30 days prior to inclusion
- •age < 30years
- •contraindication for MRI (cardiac pacemaker, certain metal implants, claustrophobia
- •known allergies to contrast CT or MRI contrast media
- •patients with an glomerular filtration rate of < 60ml/min/1.73m2
结局指标
主要结局
Measurement of blood flow, blood volume and transfer constant (Ktrans) with CT-Perfusion and PET/MR-perfusion in solid tumors.
时间窗: 18 months
次要结局
- Correlation of blood flow, blood volume and transfer constant (Ktrans) measured with CT-Perfusion and PET/MR-perfusion with progression free survival in solid tumors.(18 months)
研究者
研究点 (1)
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