PET/MRI Perfusion and CT Perfusion in Solid Tumors
Terminated
- Conditions
- CT Perfusion and MRI Perfusion in Solid Tumors
- Registration Number
- NCT02314962
- Lead Sponsor
- University of Zurich
- Brief Summary
Diagnostic comparison between PET/CT and PET/MRI with integrated perfusion measurement in CT and MR. Study aim is to gain knowledge about additional value of CT perfusion and MR perfusion in solid tumors concerning tumor physiology, diagnostic accuracy and possibly prognostic.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 43
Inclusion Criteria
- indication as stated above
- written informed consent
- patients with suspected or confirmed solid malignant tumors of the neck, chest or abdomen who have an indication for a PET/CT
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Exclusion Criteria
- pregnant or breast feeding women
- non compliance of the patient to follow the study instructions (e.g. hearing problems, dementia)
- Inclusion in another clinical trial 30 days prior to inclusion
- age < 30years
- contraindication for MRI (cardiac pacemaker, certain metal implants, claustrophobia
- known allergies to contrast CT or MRI contrast media
- patients with an glomerular filtration rate of < 60ml/min/1.73m2
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measurement of blood flow, blood volume and transfer constant (Ktrans) with CT-Perfusion and PET/MR-perfusion in solid tumors. 18 months
- Secondary Outcome Measures
Name Time Method Correlation of blood flow, blood volume and transfer constant (Ktrans) measured with CT-Perfusion and PET/MR-perfusion with progression free survival in solid tumors. 18 months
Trial Locations
- Locations (1)
University Hospital Zurich, Diagnostic and Interventional Radiology
🇨ðŸ‡Zurich, ZH, Switzerland