Prefrontal Cortex Activity During Real-time Walking in Acute Stroke: Effects of Walking and Cognitive Functio

Not Applicable

• Conditions: Acute stroke

• Registration Number: JPRN-UMIN000050859
• Lead Sponsor: Kobe City Medical Center General Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-04-16
• Last Update Posted: 17 October 2023
• Study Completion: 2024-03-31

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

Not provided

Exclusion Criteria

Acute stroke patients 1. patients with cognitive impairment (MMSE < 21) 2. patients with neurological diseases other than post-stroke sequelae 3. patients with uncontrolled hypertension 4. patients with leg pain to the extent that it interferes with walking 5. patients with severe obesity (BMI > 40) 6. congestive heart failure, severe valvular disease, history of cardiac arrest, presence of an implantable cardioverter-defibrillator, uncontrolled angina or other macrovascular disease, and history of myocardial infarction or cardiac surgery within 1 year 7. patients on corticosteroids 8. patients with respiratory disease requiring oxygen therapy 9. Patients with renal disease requiring dialysis 10. patients with significant visual or vestibular disturbances that affect safe ambulation 11. patients with lower motor neuron impairment 12. patients with fractures or artifacts within 6 months 12. patients who have had a fracture or joint replacement within the past 6 months 13. patients with terminal cancer 14. patients who are deemed inappropriate for participation in the study by the principal investigator or study investigators. healthy elderly 1. with cognitive impairment (MMSE < 21) 2. with neurological disease 3. with mental illness 4. who have a disease that affects mobility

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
oxyhemoglobin concentration in the prefrontal cortex during each task will be measured using functional near infrared spectroscopy in acute stroke patients within 14 days of onset and healthy elderly subjects.