Investigation of Combined Treatment of Acupuncture and Neurofeedback for Improving Cognitive Function in Mild Neurocognitive Disorder

Not Applicable

Completed

• Conditions: Mental and behavioural disorders

• Registration Number: KCT0004972
• Lead Sponsor: Daejeon Korean Medicine Hospital of Daejeon University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2022-02-18
• Last Update Posted: 4 April 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 44

Inclusion Criteria

1) Mild Neurocognitive Disorder patients who meet Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5) criteria
2) Korean version of Montreal Cognitive Assessment (MoCA-K) scores less than 22
3) Education level of more than 6 years
4) Participants who understood the purpose of this study and voluntarily signed the informed consent form

Exclusion Criteria

1) Alzheimer, vascular dementia, Parkinson's disease, huntington's disease, hydrocephalus
2) Presenting mental disorder including schizophrenia, delusional disorder, major depressive disorder, bipolar disorder, alcohol dependence, substance-related disorders, and etc. based on DSM-5
3) Presence or history of neurological disorders, including epilepsy, regional brain damage, head injury, stroke, and etc.
4) Receiving treatments or participating other clinical study within the last 4 weeks due to Mild Neurocognitive Disorder
5) Having test for Mild Neurocognitive Disorder within the last 12 weeks
6) Pregnant or lactating women
7) Unstable medical state (assessment by research doctor with vital signs, laboratory test, ECG test)
8) Hypertension, blood pressure excessing 160mmHg systolic and 95mmHg diastolic
9) Significant liver disease or excessing serum AST, ALT, ?-GTP levels than twice over references
10) Unavailable to measure f-NIRS
11) Disagreement with acupuncture treatment
12) Participant, who is probably uncooperative in the study or judged by researcher as difficult to finish the study

Study & Design

• Study Type: Interventional Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Korean version of Montreal Cognitive Assessment (MoCA-K) score

Secondary Outcome Measures

Name	Time	Method
Korean version of Beck's Depression Inventory (K-BDI) score;The Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-cog) score;Oxy-Hb and deOxy-Hb in frontal lobe measured by functional Near-Infrared Spectroscopy (fNIRS);Accuracy of working memory task