Analysis of Hypertensive Disorders of Pregnancy in ICU

Not yet recruiting

Conditions: Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium, (2) ICD-10 Condition: O94||Sequelae of complication of pregnancy, childbirth, and the puerperium, (3) ICD-10 Condition: O099||Supervision of high risk pregnancy, unspecified,

Registration Number: CTRI/2023/07/054602

Lead Sponsor: Lokmanya Tilak Municipal College and Hospital sion west Mumbai 400022

Brief Summary: Despite advances in obstetric care, Hypertensive disorders of pregnancy (HDP), particularly preeclampsia/ eclampsia , remains one of the leading causes of maternal morbidity and mortality worldwide. HDP occur in 5 - 10 % of pregnancies account for nearly 18% of all maternal deaths worldwide. The World Health Organization estimates that at least one woman dies every 7 min from the complications of Hypertensive disorder of pregnancy. In India, HDP accounts for the third most important cause of maternal mortality. The pregnant woman is usually young and in good health before she becomes critically ill; hence, her prognosis will be better if she receives timely intensive care intervention. Quite often, the Intensive Care Unit (ICU) intervention becomes necessary for the treatment of hypertensive disorder of pregnancy particularly, preeclampsia/eclampsia for the management of associated complications but even then HDP is the leading cause maternal death in developed but more so developing country.

Primary prevention of HDP and its complications is not always possible. Many a times delivery is only option to reduce maternal as well as perinatal morbidity and mortality .Caesarean section is preferred mode of delivery. Thus anesthetist plays a major role not only in perioperative management of HDP

women coming Caesarean section but also in their critical care in postoperative ICU as delivery only initiates the recovery but it is not a cure .

The rising incidence of HDP-related deaths makes it necessary to identify the causes of such mortalities and provide this information to healthcare providers to protect these mothers from death in an intensive care unit. However, there are very few data specifically concerning HDP patients transferred to intensive care unit.

Thus we decided undertake this study to compare Caesarean operated obstetric patients admitted in ICU with and without HDP with respect to morbidity and mortality and to compare factors to identify predictors of maternal morbidity & mortality in HDP

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: Female

Target Recruitment: 60

Inclusion Criteria

All caesarean operated obstetric patients admitted in ICU postoperative within 6 weeks of termination of pregnancy will be enrolled in the study.

Exclusion Criteria

Any Obstetric patients who did not undergo cesarean delivery or not admitted to ICU will not be included in this study.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
4.Mortality	Upto 6 weeks post operative period
1.Indication of admission to ICU	Upto 6 weeks post operative period
Primary objectives: Comparison of post caesarean operated obstetric patients with & without Hypertensive disorders of pregnancy with respect to :	Upto 6 weeks post operative period
2.Morbidity with respect to organ dysfunction	Upto 6 weeks post operative period
3.Morbidity with respect to critical intervention	Upto 6 weeks post operative period

Secondary Outcome Measures

Name	Time	Method
Secondary Objective: To find association of factors in post caesarean operated patients admitted to ICU with Hypertensive disorders of pregnancy with 1. Maternal morbidity,	2. Maternal mortality

Trial Locations

Locations (1): Lokmanya Tilak Municipal College
🇮🇳
Mumbai, MAHARASHTRA, India
Lokmanya Tilak Municipal College
🇮🇳Mumbai, MAHARASHTRA, India
Dr Sanjana Patil
Principal investigator
9167398352
sanjanapatil616@gmail.com