Evidence-based medicine research of tonifying qi-blood and regulating tendon and vessel on the prevention and treatment of anemia and thrombosis on added effection of enhanced recovery after surgery of total knee arthroplasty
- Conditions
- knee osteoarthritis
- Registration Number
- ITMCTR2024000070
- Lead Sponsor
- Wangjing Hospital of China Academy of Chinese Medicine Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
Subjects had to meet all of the following inclusion criteria:
(1) 50 years old = enrollment age =80 years old;
(2) patients who met the diagnosis of KOA and the indications for TKA;
(3) no previous history of thrombosis related diseases within half a year;
(4) primary unilateral TKA without contraindication;
(5) patients without thrombosis by color Doppler ultrasound before operation;
(6) able to cooperate with the follow-up and have good compliance;
(7) voluntarily participated in the trial and signed the informed consent form in person.
Subjects could not meet any of the following exclusion criteria:
(1) those who did not meet the inclusion criteria;
(2) patients with serious underlying medical diseases, including cardiopulmonary dysfunction, liver and kidney dysfunction or bone marrow hematopoietic dysfunction;
(3) patients with abnormal coagulation function;
(4) patients with allergic constitution or allergic to the drugs involved in this trial;
(5) patients with previous history of gastrointestinal bleeding and bleeding tendency;
(6) patients with severe mental illness;
(7) those who participated in other investigational drug or device clinical trials within the past 3 months;
(8) other situations considered by the investigators to be inappropriate for this clinical study.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method