Specimen Repository for HIV Immunopathogenesis
Completed
- Conditions
- Acute HIV InfectionHIV-1-infection
- Registration Number
- NCT03579381
- Lead Sponsor
- AIDS Healthcare Foundation
- Brief Summary
Specimen Repository for HIV Immunopathogenesis Studies
- Detailed Description
The goal is to build a large specimen repository for collaborating scientists to run studies of immunity and HIV-1.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 9
Inclusion Criteria
- HIV positive (acutely infected, viremic and elite controllers)
- Signed Informed Consent Form
- Age at least 18 years old
- Immune controllers, two types: "Elite suppressors" (HIV-positive with any three consecutive plasma HIV-1 RNA PCR undetectable while off treatment) or "viremic suppressors" (HIV-positive with any three consecutive HIV-1 RNA PCR <3000 while off treatment).
- Acutely infected subjects:
Persons identified to have a negative HIV antibody response (ELISA) but positive detection of HIV-1 in the blood (RT-PCR) or individuals who have evidence of a recent (past 30 days) HIV negative result along with a current HIV positive result.
Exclusion Criteria
- Uncontrolled bleeding diathesis.
- Pregnant.
- Inability to provide informed consent.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method HIV progression and control by elite and viremic suppressors 2 years Outcomes will depend on scientists who use the samples for study
HIV progression from acute infection to viral suppression 2 years Outcomes will depend on scientists who use the samples for further study
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
AIDS Healthcare Foundation - Public Health Division
🇺🇸Los Angeles, California, United States