Comparison of effectiveness of dexmedetomidine plus Midazolam and fentanyl plus Midazolam in placement of central venous catheter in PIC

Phase 3

Recruiting

• Conditions: Condition 1: Viral infection. Condition 2: Acute lower respiratory infection. Condition 3: Virus infections of central nervous system. Condition 4: Immunodeficiency. Condition 5: Renal failure requiring dialysis or plasmaphresis.; Viral infection of unspecified site; Unspecified acute lower respiratory infection; Atypical virus infections of central nervous system; Immunodeficiency, unspecified; Congenital renal failure; D84.9; P96.0

• Registration Number: IRCT20230701058628N2
• Lead Sponsor: Mazandaran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 August 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Children needing central venous catheter placement in the pediatric intensive care unit

Exclusion Criteria

Presence of bradycardia or hypotension
High blood pressure above the 99th percentile
Apnea before the study
The presence of cardiac conduction disorder in the electrocardiogram before drug administration
Patients with American Society of Anaesthesiologists' physical status classification III or higher
Known kidney or heart failure
History of heart surgery
Shock
Receiving other anesthetics, sedatives, injectable painkillers

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Ramsay Sedation Score equal to or more than 3. Timepoint: Every 5 minutes until 5 minutes after sedation. Method of measurement: Ramsay scale.;Mean arterial blood pressure. Timepoint: Every 5 minutes until 5 minutes after sedation. Method of measurement: Blood pressure monitor.;Blood oxygen saturation. Timepoint: Every 5 minutes until 5 minutes after sedation. Method of measurement: Palsoxymeter.;Heart rate and respiratory rate. Timepoint: Every 5 minutes until 5 minutes after sedation. Method of measurement: ????? ?? ?????.