Finding the Optimal Resistance Training Exercise for type 2 diabetes

Completed

• Conditions: Type 2 diabetes; Nutritional, Metabolic, Endocrine; Non-insulin-dependent diabetes mellitus

• Registration Number: ISRCTN97865321
• Lead Sponsor: Toronto Rehabilitation Institute (Canada)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-06-21
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

1. Adults aged greater than 18 years, either sex
2. Type 2 Diabetes
3. Participating in the Diabetes Exercise and Healthy Lifestyle Program of the Toronto Rehabilitation Institute

Exclusion Criteria

1. History of diagnosed cardiovascular disease
2. Contraindications to high intensity exercise participation:
2.1. Glaucoma
2.2. Retinopathy
2.3. Musculoskeletal limitations
2.4. Kidney disease
2.5. Balance impairments

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Measured at baseline and 6 months:<br>1. HbA1c<br>2. Maximal aerobic power (VO2 max)

Secondary Outcome Measures

Name	Time	Method
Measured at baseline and 6 months:<br>1. Fasting glucose<br>2. Insulin<br>3. Proinsulin<br>4. Blood lipid profile<br>5. Body composition (dual energy x-ray absorptiometry [DEXA])<br>6. Cytokines (interleukin-6 [IL-6], interleukin-1B [IL-1B], c-reactive protein [CRP])<br>7. Adipokines (tumour necrotising factor-alpha [TNF-alpha], adiponectin, leptin, leptin receptor)<br>8. Depressive mood (Center for Epidemiologic Studies Depression Scale [CESD])<br>9. Quality of life (Diabetes Quality of Life Clinical Trial Questionnaire [DSQLQ])<br>10. Nutrition intake