The Role of POLE Mutation in High Risk Endometrial Cancer.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Prevalence of POLE mutation in high risk endometrial cancer
研究概览
简要总结
The actual role of POLE mutations in high-risk endometrial cancer is undetermined. The main question it aims to answer is:
What is the prevalence of POLE mutations in high-risk endometrial cancer case? What is the impact of POLE mutations in real world high-risk endometrial cancer case?
详细描述
All high-risk recurrent endometrial cancer cases who were treated in a tertiary referral center will be analyzed and subjected to POLE mutation analysis. In addition, survival analysis will be used to analyze the role of POLE mutations in women with high-risk endometrial cancer. We can answers the following.
- What is the prevalence of POLE mutations in women with high-risk endometrial cancer?
- What is the role of POLE mutations in real world high-risk endometrial cancer?
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •women with high-risk for recurrent endometrial cancer
排除标准
- 未提供
结局指标
主要结局
Prevalence of POLE mutation in high risk endometrial cancer
时间窗: 2 years
The prevalence of POLE mutations in women with high-risk for recurrent endometrial cancer
次要结局
- The impact of POLE on overall survival(5 years)
研究者
Sheng-Mou Hsiao
Chief, Department of Obstetrics & Gynecology
Far Eastern Memorial Hospital