Efficasy of transcranial direct current stimulation on dorsolateral prefrontal cortex on BDNF, IL-6, TNF-alpha
Not Applicable
Recruiting
- Conditions
- Mental and behavioural disorders due to use of opioids.Opioid abuse with opioid-induced mood disorder
- Registration Number
- IRCT20170513033946N5
- Lead Sponsor
- Zanjan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Male
- Target Recruitment
- 36
Inclusion Criteria
Having informed consent to participate in the research
Methadone treatment for at least two weeks before the intervention
Age 18- 50 years old
Minimum grade education
Exclusion Criteria
The absence of more than two sessions
Suicidal thoughts or dangers that It is not possible to keep the dosage fixed
Having severe psychiatric disorders such as schizophrenia
Consuming multiple substance
History of injury to the head
History of epileptic seizures
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Brain- derived neurotrophic factor (BDNF). Timepoint: pretest-post test. Method of measurement: Eliza kit.
- Secondary Outcome Measures
Name Time Method Interleukin 6 (IL-6). Timepoint: pretest-post test. Method of measurement: Eliza kit.;Tumor necrosis factor-( TNF-a). Timepoint: pretest-post test. Method of measurement: Eliza kit.;Quantitative EEG (QEEG). Timepoint: pretest-post test. Method of measurement: Mitsar set.;BART Impassivity. Timepoint: pretest- post test. Method of measurement: BART Impassivity questionnaire.;Craving. Timepoint: pretest- post test. Method of measurement: Desires for Drugs Questionnaire (DDQ).;Sub scale anxiety -DASS. Timepoint: pretest- post test. Method of measurement: depression sub scale(DASS).;Decision making ablity. Timepoint: pretest-post test. Method of measurement: IUWA Gambling Task.