A clinical trial to study the effectiveness of transcranial direct current stimulation (A very low current brain stimulation) on upper limb movement control in stroke patients.
- Conditions
- Health Condition 1: null- Cerebrovascular accident (Stroke)
- Registration Number
- CTRI/2018/04/013178
- Lead Sponsor
- D Subramanian
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 41
1. Medically stable participants
2. Cortical or subcortical area lesion supplied by middle cerebral artery, Anterior cerebral artery, Posterior cerebral artery and confirmed by MRI / CT
3. Early or late subacute stage (1- 6 months)
4. Ischemic or hemorrhagic stroke
5. Arm paresis with Chedoke McMaster Arm Score of 2-6 out of 7 and Hand score of 2-6 out of 7.
6. Recurrent stroke with completely recovered previous stroke.
1. Major neurological (other than stroke) / neuromuscular / orthopaedic problems
2.Major cognitive deficits
3.History of psychiatric disorders,seizure, migraine within last six months
4. Metal in cranium and other implants (cochlear, cardiac)
5. Skin sensitivity
6. Participants taking medications that could affect brain activity (e.g. epileptic and psychoactive drugs)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. kinematic Analysis ( reach-to-grasp standardized Test Task) <br/ ><br>2. Montreal Tonic stretch threshold measure (Spatial zones) <br/ ><br>3. Chedoke Arm and Hand Activity Inventory (CAHAI- 7 Version) <br/ ><br>4. Action Research Arm Test (ARAT) <br/ ><br>Timepoint: 0 weeks, 4 weeks and 8 weeks
- Secondary Outcome Measures
Name Time Method 1. Reaching Performance Scale <br/ ><br>2. Composite spasticity Index <br/ ><br>3. Upper Extremity Subset of Fugl – Meyer Motor Function Assessment (UE –FMA) <br/ ><br>4. Patient Health Questionnaire-9Timepoint: 0 weeks, 4 weeks and 8 weeks