MS Mosaic: A Longitudinal Research Study on Multiple Sclerosis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 2,200
- 试验地点
- 1
- 主要终点
- Change in perceived fatigue severity (self-report) as recorded by symptom diary
研究概览
简要总结
The purpose of this study is to better characterize the fluctuations in multiple sclerosis symptoms and their relationship to medications, to length/extent of disease, and to a variety of physiologic measures.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Be at least 18 years old
- •Live in the United States of America
- •Read/write in English
排除标准
- 未提供
结局指标
主要结局
Change in perceived fatigue severity (self-report) as recorded by symptom diary
时间窗: Every 24 hours through study completion, an average of 6 months
Change in perceived cognitive impairment (self-report) as recorded by symptom diary
时间窗: Every 24 hours through study completion, an average of 6 months
Severity of cognitive impairment experienced from multiple sclerosis
Change in perceived depression or anxiety severity (self-report) as recorded by symptom diary
时间窗: Every 24 hours through study completion, an average of 6 months
Severity of any mood disorders experienced from multiple sclerosis
次要结局
- Change in perceived walking instability (self-report) as recorded by symptom diary(Every 24 hours through study completion, an average of 6 months)
- Change in perceived vision difficulties (self-report) as recorded by symptom diary(Every 24 hours through study completion, an average of 6 months)
- Change in perceived Bowel/Bladder dysfunction (self-report) as recorded by symptom diary(Every 24 hours through study completion, an average of 6 months)
- Change in perceived sensory disturbance (self-report) as recorded by symptom diary(Every 24 hours through study completion, an average of 6 months)
- Change in perceived vertigo severity (self-report) as recorded by symptom diary(Every 24 hours through study completion, an average of 6 months)
- Change in perceived dysarthria severity (self-report) as recorded by symptom diary(Every 24 hours through study completion, an average of 6 months)
- Change in pain (self-report) as recorded by symptom diary(Every 24 hours through study completion, an average of 6 months)
- Change in sleep quality as recorded by app-linked wearable device(Every 24 hours through study completion, an average of 6 months)
- Change in medication adherence (self-report) as recorded by medication diary(Every 24 hours through study completion, an average of 6 months)
- Change in self-efficacy (self-report) as determined by the Multiple Sclerosis self-efficacy scale (survey instrument)(every three months, through study completion (an average of 6 months))
- Change in Multiple Sclerosis Quality of Life Inventory(prompted based on the app user's responses on the daily surveys, up to 6 months)