Evaluation of endothelial function and cardiac autonomic and this relationship with clinical and functional aspects in patients with isolated chronic obstructive pulmonary disease and the coexistence of heart failure in exacerbation phase.

Not Applicable

Recruiting

• Conditions: Chronic Obstrutive Pulmonary Disease; Heart Failure; J44.1

• Registration Number: RBR-5778vq
• Lead Sponsor: niversidade Federal de São Carlos

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-03-24
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

CCOPD patients; pulmonary function test values with forced expiratory volume in the first second (FEV1) / forced vital capacity (FVC) less than 0.7 and FEV1 less than 80% of predicted; associated with a history of drug treatment and signs and symptoms of COPD exacerbation;
Typical HF signs and symptoms combined with a reduction in left ventricular (EF) fraction less than 50% by Doppler Echo, with forced expiratory volume in the first second (FEV1) / forced vital capacity (FVC) less than 0, 7 and lower FEV1 than 80% of the forecast).

Exclusion Criteria

Alcoholic patients and / or drug users who cause chemical dependency; patients using invasive mechanical ventilation; hemodynamic instability; presence of unstable angina; history of myocardial infarction in the last 6 months; patients who exacerbate again within the 30-day period.

Study & Design

• Study Type: Intervention
• Study Design: Not specified