The Sex Hormones And Physical Exercise study

Completed

• Conditions: Reducing the risk of breast cancer; Cancer

• Registration Number: ISRCTN11633173
• Lead Sponsor: The National Cancer Fund (Koningin Wilhelmina Fonds [KWF]) (The Netherlands)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2006-09-26
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 189

Inclusion Criteria

1. Women aged 50 to 69 years
2. More than 12 months since last menses
3. Non-smokers (at least 12 months)
4. Sedentary: less than two hours per week of moderate sport activity (e.g. tennis, swimming, running, aerobics, fitness, volleyball) and not adherent to the international physical activity guideline. The international physical activity guideline states that every adult should accumulate 30 minutes or more of at least moderately intense physical activity for at least five days per week
4. Knowledge of the Dutch language
5. Agreement to be randomly assigned to either the exercise intervention or control group
6. Informed consent to participate in all screening and study activities

Exclusion Criteria

1. Use of hormone replacement or oral contraceptives in past six months
2. Morbidly obese (Body Mass Index [BMI] more than 40)
3. BMI less than 22
4. Currently on or planning to go on a strict diet
5. Ever diagnosed with breast cancer
6. Diagnosis of other types of cancer in the past five years
7. Diabetes mellitus or other endocrine related diseases
8. Disorders or diseases (locomotor, optical, neurological, mental) that might impede the participation in the exercise programme
9. Alcohol or drug abuse
10. Maintenance use of corticosteroids
11. Use of beta blockers

Study & Design

• Study Type: Interventional
• Study Design: Not specified