evofloxacin in treatment of tuberculosis infection of brain in childre

Phase 2

• Conditions: Health Condition 1: A170- Tuberculous meningitis

• Registration Number: CTRI/2024/07/070282
• Lead Sponsor: All India Institute of Medical Sciences, Rishikesh

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 22 July 2024

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Diagnosed cases of tubercular meningitis presenting to Department of Pediatrics, All India Institute Medical Sciences, Rishikesh with a diagnosis of TB meningitis as per Marais’ criteria and parents willing to comply with the study protocol and follow up

Exclusion Criteria

Pre-existing major chronic systemic illness including cardiovascular (arrhythmia, prolonged QTc interval or history of any arrhythmia), respiratory (chronic lung disease), gastrointestinal system (chronic liver disease) or chronic renal disease

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Functional Status ScaleTimepoint: 12 weeks

Secondary Outcome Measures

Name	Time	Method
Childhood Behavioural Checklist internalizing, externalizing and total scoreTimepoint: 12 weeks;Duration of hospitalisationTimepoint: At diagnosis;Functional status scaleTimepoint: 12 weeks;Number of patients with paradoxical reactionTimepoint: within 12 weeks;Pediatric Cerebral Performance CategoryTimepoint: 12 weeks;Social quotient by Vineland Social Maturity ScaleTimepoint: 12 weeks;SurvivalTimepoint: 12 weeks